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Author: Admin | 2025-04-28
What is Tramadol?Tramadol is an opioid that’s most often prescribed to treat pain. Available in immediate- and extended-release formulations, tramadol is also offered in combination with acetaminophen.1,2 Tramadol hydrocholoride and tramadol hydrochloride/acetaminophen combinations are sold as a generics, but other names for tramadol include the following brands: ConZip, Qdolo, and Seglentis.2Does tramadol get you high, and can tramadol be addictive?Although it has valid therapeutic effects, tramadol is sometimes misused for its rewarding opioid effects, which can include euphoria and feelings of relaxation (aka a tramadol high).3 And while tramadol is classified as a Schedule IV drug with low potential for misuse and risk of dependence, its drug label warns that use exposes people to the risks of misuse and addiction.1,4Data from the 2022 National Survey on Drug Use and Health shows that of the 14.6 million people aged 12 and older who used tramadol products in the past year, 9.4% of these individuals misused the drug.5 An estimated 6.1 million people in that same age group had an opioid use disorder in the past year.6How Tramadol Affects the BrainLike other opioids, tramadol modifies pain signals by attaching to and activating opioid receptors throughout the brain. This activation is associated with an increase in dopamine activity in key regions of the brain, which can significantly reinforce the act of taking drugs such as tramadol and ultimately prompt people to repeat the experience.3Tramadol Side Effects and Adverse Events Associated with MisuseWhile tramadol is an effective pain reliever, it has several potential side
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