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Author: Admin | 2025-04-28
HomeDurolaneSide Effects Generic name: sodium hyaluronateMedically reviewed by Drugs.com. Last updated on Apr 3, 2024. Other side effectsSerious side effectsProfessional info Note: This document provides detailed information about Durolane Side Effects associated with sodium hyaluronate. Some dosage forms listed on this page may not apply specifically to the brand name Durolane.Applies to sodium hyaluronate: injection gel/jelly, injection solution.Common side effects of DurolaneSome side effects of sodium hyaluronate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: More common side effects diarrheaheadache itching of the skinlarge, nonelevated blue or purplish patches in the skinloss of appetitenausea and/or vomitingstomach pain swelling of the knee Serious side effects of DurolaneAlong with its needed effects, sodium hyaluronate (the active ingredient contained in Durolane) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking sodium hyaluronate: Less common side effects blue color or flushing or redness of skin coughdifficulty in swallowing dizziness or feeling faint (severe)feverredness or pain at place of injection skin rash, hives, and/or itchingstuffy noseswelling of eyelids, face, or lips tightness in chest, troubled breathing, and/or wheezing For healthcare professionalsApplies to sodium hyaluronate: injectable gel, intra-articular solution.Local adverse eventsCommon (1% to 10%): Injection site pain/swelling/effusion/redness/warmthUncommon (0.1% to 1%):[Ref]HypersensitivityFrequency not reported: Hayfever reaction on face and neck, reaction on forearms and kneesPostmarketing reports: Anaphylaxis/anaphylactoid reaction[Ref]OtherFrequency not reported: Swelling of the face/eyelids/mouth/extremities, fever[Ref]GastrointestinalCommon (1% to 10%): Nausea, vomiting, abdominal pain, diarrhea, dyspepsia[Ref]CardiovascularFrequency not reported: Transient hypotension[Ref]MusculoskeletalVery common (10% or more): Arthralgia (18%), arthropathy/arthrosis/arthritis (11%)Common (1% to 10%): Back pain, leg discomfort, leg pain[Ref]ImmunologicCommon (1% to 10%): Influenza-like reaction[Ref]GenitourinaryCommon (1% to 10%): Urinary tract infection[Ref]RespiratoryCommon (1% to 10%): Upper respiratory tract infection, sinusitis, bronchitis, rhinitis[Ref]Nervous systemCommon (1% to 10%): Headache, dizziness[Ref]DermatologicFrequency not reported: Rash, itching[Ref]References1. "Product Information. Hyalgan (sodium hyaluronate)." Sanofi Winthrop Pharmaceuticals2. (2001) "Product Information. Supartz (sodium hyaluronate)." Smith and Nephew Wound Management DivisionFurther informationDurolane side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.Medical Disclaimer
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