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Author: Admin | 2025-04-28
HomeTreatmentsMetabolic DisordersWeight Loss (Obesity/Overweight) Other names: anorexiants; anti-obesity medications; diet drugs; diet medications; Weight Loss Medications Common weight loss medications (anorexiants) are benzphetamine (Didrex, Regimex), bupropion and naltrexone (Contrave), diethylpropion, liraglutide (Saxenda), methamphetamine (Desoxyn), orlistat (alli, Xenical), phendimetrazine (Bontril, Melfiat), phentermine (Adipex-P, Lomaira), phentermine and topiramate (Qsymia), semaglutide (Wegovy), and tirzepatide (Zepbound). Sibutramine (Meridia) was withdrawn from U.S. market in 2010 due to increased heart toxicity risk, and lorcaserin (Belviq) was withdrawn from the U.S. market in 2020 due to an increased cancer risk.Weight loss medications are usually used together with a reduced calorie diet and and exercise.Table of Common Weight Loss Drugs Brand Name (Manufacturer) Generic Name Description Controlled Substance? Adipex-P Lomaira phentermine oral tablet or capsules; appetite suppressant; anorectic yes, C- IV alli, Xenical orlistat oral capsule; lipase inhibitor; inhibits fat absorption in the intestine available over-the-counter (OTC) Belviq, Belviq XR (brands and generic discontinued) lorcaserin (withdrawn) selective serotonin 2C receptor agonist; promotes a feeling of fullness or satiety; withdrawn from US market in 2020 due to increased cancer risk (such as pancreatic, colorectal, and lung). product withdrawn Bontril PDM, Melfiat (both brands discontinued) phendimetrazine oral tablets; appetite suppressant; anorectic yes, C-III Desoxyn methamphetamine oral tablets; appetite suppressant; use cautiously if prescribed for weight loss due to high potential for abuse, illegal distribution yes, C-II Didrex, Regimex (both brands discontinued) benzphetamine oral tablet; appetite suppressant; anorectic yes, C-III Tenuate, Tenuate Dospan (brands discontinued) diethylpropion oral tablet; appetite suppressant; anorectic yes, C-IV Meridia (brand discontinued) sibutramine (withdrawn) anorectic; withdrawn from US market in 2010 due to increased heart toxicity risk. product withdrawn Qsymia phentermine and topiramate extended-release oral capsules; combination appetite suppressant-anorectic; exact action of topiramate on weight loss is not known yes, C-IV Suprenza (brand discontinued) phentermine oral tablet; appetite suppressant; anorectic brand not available; generic C-IV Xenical orlistat oral capsule; lipase inhibitor; prescription form of Alli (OTC); higher dose than Alli; inhibits fat absorption in the intestine not controlled; prescription required. Contrave bupropion and naltrexone oral tablet; increases metabolism, suppresses appetite, affects central reward center (proposed mechanism) not controlled; prescription required. Saxenda liraglutide once-daily subcutaneous injection; glucagon-like
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