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Author: Admin | 2025-04-28
Tarry stools (melena) or vomiting blood (hematemesis).Perforation: In severe cases, ulcers can perforate (create a hole) through the stomach or intestinal wall, resulting in a life-threatening condition called peritonitis.Abdominal Pain: The dog may display signs of severe abdominal discomfort, such as restlessness, whining, or a hunched posture.Renal DamageKidney Failure: Ibuprofen is particularly toxic to canine kidneys. This damage can initially present as increased thirst and urination, but can rapidly progress to kidney failure with a sudden decrease in urine output.Renal Dysfunction: Impaired kidney function can lead to a build-up of toxins in the blood.Neurological SignsDisorientation: Your dog may appear confused, unable to navigate properly, or appear lost.Loss of Motor Coordination: Ataxia (uncoordinated movement) may become apparent, with the dog appearing wobbly or unbalanced.Seizures: In massive doses (usually around 400 mg/kg), ibuprofen can cause seizures, a very serious sign of central nervous system involvement.Coma: In the most severe cases, the dog can fall into a coma.Long-Term ComplicationsEven if a dog survives the initial stages of ibuprofen toxicity, long-term consequences can occur:Chronic Kidney Disease (CKD): Kidney damage from ibuprofen can be irreversible and can progress to CKD, requiring lifelong management.Persistent Gastrointestinal Problems: Dogs may experience chronic gastritis, recurrent ulcers, or other digestive issues.Liver Damage: Though less common, ibuprofen can also potentially affect liver function.Why a 400mg Dose is DangerousThe critical point to understand is that dogs have a very low tolerance for ibuprofen. The toxic dose for dogs varies based on their size, but even a small amount can be dangerous. The article provided states that, for example, a 15 kg dog can become toxic with 375 mg, and that signs can occur with half a 200 mg pill for a 25-pound dog. A 400 mg dose, especially for a small or medium-sized dog, far exceeds the threshold for causing severe, even lethal, reactions. Never attempt to give your dog ibuprofen in any dose.What To Do If Your Dog Eats 400mg of IbuprofenIf you know or suspect your dog has ingested 400 mg of ibuprofen, immediate veterinary intervention is absolutely essential. Time is of the essence in these cases.Contact your veterinarian immediately: Do not wait to see if symptoms appear. Call your vet, or the nearest emergency animal clinic, and inform them of what happened, how much your dog ingested, and their size/weight if known.Do not induce vomiting at home: It is safer to let your vet assess the situation and decide if vomiting should be induced. Some animals are not candidates for induced vomiting.Follow your vet’s instructions carefully: They will likely want to examine your dog, start treatment, and monitor their condition closely.Treatment will likely involve:Induced vomiting: If the ingestion has been recent (usually within 1-2 hours), your vet may induce
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