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Author: Admin | 2025-04-28
Wellbutrin (bupropion) is a prescription drug used for certain mental health conditions. The drug comes in two forms:Wellbutrin XL is used to treat depression and help prevent seasonal affective disorder in adults.Wellbutrin SR is used to treat depression in adults.This article covers both Wellbutrin XL and Wellbutrin SR, and uses the term “Wellbutrin” to refer to both forms.Like other drugs, Wellbutrin may have interactions. Interactions are expected to be the same for both forms of Wellbutrin.Some interactions occur because one substance causes another substance to have a different effect than expected. For example, alcohol, another drug, or a supplement can affect how a drug acts in your body. Interactions can also occur if you have certain health conditions.Keep reading to learn about Wellbutrin’s possible interactions. And for more information about Wellbutrin, including details about its uses, see this article.Certain health conditions or other factors could raise your risk of harm if you take Wellbutrin. In such cases, your doctor may not prescribe Wellbutrin for you. These are known as contraindications. The list below includes contraindications of Wellbutrin.If you have seizures. Wellbutrin can cause seizures in rare cases. You should not take Wellbutrin if you have epilepsy (seizure disorder), another condition that causes seizures, or are taking other drugs that can raise your risk of a seizure. Instead, talk with your doctor about safer treatments for your condition.If you’ve been diagnosed with an eating disorder before. Studies showed an increased risk of seizures in people who took Wellbutrin and had also been diagnosed with anorexia or bulimia. Because of this risk, doctors will avoid prescribing Wellbutrin if you’ve been diagnosed with either condition.If you recently suddenly stopped using alcohol or certain drugs. Wellbutrin can cause seizures in rare cases. Your risk of a seizure with Wellbutrin may be higher if you’ve recently stopped taking certain drugs, including a benzodiazepine, barbiturate, or epilepsy drug. This risk may also be higher if you’ve suddenly stopped drinking alcohol (and you used to drink regularly or excessively). You should not take Wellbutrin if you’ve recently stopped using alcohol or one of these drugs suddenly.If you take a monoamine oxidase inhibitor (MAOI) drug. Taking an MAOI drug with Wellbutrin raises your risk of high blood pressure. (MAOIs are a kind of antidepressant, like Wellbutrin. But Wellbutrin isn’t an MAOI.)This interaction can occur between Wellbutrin and any MAOI. A few examples of MAOIs include:selegiline (Emsam, Zelapar)isocarboxazid (Marplan)linezolid (Zyvox)phenelzine (Nardil)methylene blue (Provayblue)Because of this risk, doctors will avoid prescribing Wellbutrin with an MAOI. If you’re taking an MAOI, your doctor will have you stop taking it at least 14 days before you start treatment with Wellbutrin.If you have other questions about Wellbutrin and MAOIs, talk with your doctor
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