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Author: Admin | 2025-04-28
Oil is one of the most popular CBD delivery methods for therapeutic purposes because it offers a fast onset and flexible dosing.Research on Gabapentin for Nerve PainGabapentin was first approved by the Food and Drug Administration (FDA) in the mid-1990s, and many studies indicate that it has the ability to reduce nerve pain.One research review looked at 530 patients who had either postherpetic neuralgia (related to shingles) or painful diabetic neuropathy. Patients of postherpetic neuralgia experienced twice as much pain relief when given gabapentin versus a placebo (dummy non-medicine substance), and patients of painful diabetic neuropathy experienced 1.5 times as much pain relief when given gabapentin versus a placebo [1]. There are many other studies that show similar results; this is just an example of what research says about the pain-relieving benefits of gabapentin. Research on CBD Oil for Nerve PainWhile CBD oil isn’t a proven treatment for nerve pain, preliminary research suggests CBD and cannabis products have therapeutic potential for this use.In a 2020 study, University of Washington researchers examined the effects of CBD on pain caused by sciatic nerve injury. Researchers concluded that cannabinoids have the potential to provide “long-term relief of chronic pain states” for people with this condition [2]. Another study investigated the benefits of CBD for nerve pain. The researchers found that CBD helped to reduce the amount of gabapentin that patients needed to take.The researchers also found that neuropathic pain patients using any kind of cannabis-based medicine (CBD, THC, etc.), were hospitalized for fewer total days than those not using these natural supplements [3]. Anecdotally, many people use CBD for sciatica, a type of nerve pain. Based on this research, it’s clear that CBD has therapeutic potential for people dealing with nerve pain. However, more studies are needed to further confirm these results. CBD Oil vs. Gabapentin: How They Work for Nerve PainCBD and gabapentin work differently in the body to render their benefits. Here’s a bit about the mechanism of action of each:How Gabapentin worksGabapentin is an analog of gamma aminobutyric acid (GABA), a neurotransmitter in the brain. An analog is a synthetic version of something else; gabapentin is, in essence, GABA, and is designed to mirror its function in the body. GABA reduces the excitability of nerve cells (neurons) in the brain, which play a role in seizures and the transmission of pain signals. By doing the same thing, Gabapentin calms excited neurons and reduces pain.How CBD worksCBD works for nerve pain by supporting your endocannabinoid system (ECS). The ECS is a receptor system in your body that’s responsible for regulating your vital functions, including the inflammatory and pain response.Ultimately, the job of the ECS is to keep your mind and body in a state of balance and good health.There are two types of receptors in your ECS:CB1 receptors, which influence the mind if stimulatedCB2 receptors, which influence the body if stimulatedAlthough CBD doesn’t bind strongly to the CB1 or CB2 receptors as many cannabinoids do, research suggests that it supports the
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