Comment
Author: Admin | 2025-04-28
Serious side effectsMay interact with medications known to interfere with heart rhythm. Ask your pharmacist to double check to see if you are taking any of these types of interacting medicinesMay cause fetal harm if taken while pregnant. Men and women taking ivosidenib should use effective contraception during treatment and for one month after the last dose. Avoid breast feeding during ivosidenib treatment and for one month after the last doseGeneral side effects from ivosidenib (Tibsovo®)Diarrhea Increased white blood cells Nausea/vomitingFatigue Neutropenic fever Shortness of breath Low red blood cells Swelling Decreased appetite Constipation Low platelets Dizziness Nosebleed Headache Differentiation syndrome RashLow blood pressureSide Effect Videos Nausea and VomitingDiarrheaFatigue BleedingConstipationPainAnemiaNeutropenic FeverSee DailyMed package insert.Azacitidine (Vidaza®)Azacitidine is an intravenous infusion or a subcutaneous (SubQ) injection Depending upon your dose, you may receive 2 to 3 separate injections if given subcutaneously. This is because only a small amount of fluid can be administered with each subcutaneous injection. In other words, the total dose may be divided into 2 or more injections under the skinAzacitidine is very unstable when given as an intravenous infusion and must finish infusing within 1 hour after it is made.Dosage adjustments may be required for low white blood cells or low platelets General Azacitidine (Vidaza) Side Effects Commonly causes low red blood cells, white blood cells, and platelets. Good blood cells often start to increase after 3 - 4 cyclesClick on the azacitidine (Vidaza) package insert below for reported side effects and possible drug interactionsSide Effect Videos Fatigue AnemiaSee DailyMed package insert. References 1) Montesinos P, Recher C, Vives S, et al. Ivosidenib and Azacitidine in IDH1-Mutated Acute Myeloid Leukemia. N Engl J Med 2022; 386:1519-1531 Created: August 19, 2024 Updated: August 19, 2024 What is Acute Myeloid Leukemia (AML)? A disease of the myeloid cells found in the bone marrow. Myeloid cells are responsible for developing into mature white blood cells, red blood cells, and platelets. In AML, immature myeloid cells know as “blasts” replicate at a very fast rate. Sometimes blasts crowd out the normal cells in the bone marrow so that red blood cells or platelets are unable to develop. Common symptoms of this include fatigue, difficulty exercising, or easy bruising or bleeding.Most cases of AML are considered “de novo” meaning that the cause is unknown. However, there are a few known risk factors for AML, such as exposure to radiation, various environmental toxins, and
Add Comment