Myeloma criteria

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Actual: In 2025, the International Myeloma Working Group (IMWG) updated the criteria for diagnosing myeloma and added three additional criteria to the traditional Calcium elevation, Renal impairment, Anemia, Bone disease (CRAB) criteria, called the Sixty % marrow plama cells, Light chain ratio 60, Mri demonstates lytic lesions (SLiM) criteria (clonal bone marrow plasma cells
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Patients with confirmed diagnosis of relapsed or progressed multiple myeloma after first-line therapy based on the criteria established by the International Myeloma Working

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Latent Multiple Myeloma (SMM) Both criteria must be met: Serum monoclonal protein (IgG or IgA) 3 g/dl, or monoclonal urinary protein 500 mg in 24 hours and/or 10%-60% of clonal plasma cells in the bone marrow; Absence of events defining myeloma or amyloidosis. Multiple Myeloma (MM) Both criteria must be met:

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Still, in patients with high-risk smoldering myeloma, as defined by the International Myeloma Working Group diagnostic criteria, AQUILA may provide enough evidence for

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ᅟ: FDG PET/CT (18 F-fluoro-deoxy-glucose positron emission tomography/computed tomography) is a useful tool to image multiple myeloma (MM).However, simple and reproducible reporting criteria are still lacking and there is the need for harmonization. Recently, a group of Italian nuclear medicine experts defined new visual descriptive criteria (Italian Myeloma criteria

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Smoldering multiple myeloma: Both criteria must be met: Serum monoclonal protein (IgG or IgA) 3gm/dL, or urinary monoclonal protein 500 mg per 24h and/or clonal bone marrow plasma cells 10 60%. Absence of myeloma defining events or amyloidosis. Multiple Myeloma: Both criteria must be met:

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The Mayo-2025 smoldering multiple myeloma (SMM) risk score is used routinely in the clinical setting but has only been validated at diagnosis. International Myeloma Working Group. Criteria for

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Smoldering multiple myeloma is a precursor or early sign that someone may develop multiple myeloma. Not everyone who has smoldering multiple myeloma develops multiple myeloma. When healthcare providers talk about criteria, they’re talking about test results that meet medical standards for making a certain diagnosis. The criteria for SMM are:

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The C.R.A.B criteria defines certain symptoms of multiple myeloma, such as calcium elevation. They are an important tool that doctors use to help diagnose multiple myeloma and determine its

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The Italian myeloma criteria for PET use (IMPeTUs) were proposed to standardize FDG PET/CT reading in multiple myeloma. In this communication an overview on IMPeTUs is provided as well as some

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