Drugs causing metabolic acidosis

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Actual: Symptomatic patients are treated with drugs such as atropine or isoproterenol. If metabolic acidosis is the cause of bradycardia, the origin of
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Metabolic acidosis is caused by severe dehydration, drug overdoses, liver failure, carbon monoxide poisoning and other causes. Metabolic acidosis develops when the body has too much acidic ions in the blood.

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by CT Holt 2024 Cited by 6Drug causes of metabolic acidosis are numerous and their mechanisms are diverse. Broadly, they can cause metabolic acidosis with either a normal

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Metabolic acidosis is a clinical disturbance defined by a pH less than 7.35 and a low HCO3 level. The anion gap helps determine the cause of the metabolic acidosis. An elevated anion gap metabolic acidosis can be caused by salicylate toxicity, diabetic ketoacidosis, and uremia (MUDPILES).

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by CT Holt 2024 Cited by 6drug-induced lactic acidosis or pyroglutamic acidosis). This review describes the drugs that can cause or contribute to metabolic acidosis

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It is not always clear whether these conditions cause metabolic acidosis, or whether acidosis causes these conditions. Drug-induced acidosis. Some prescription medications can increase acidity

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Metabolic acidosis is common in acutely unwell patients and indicates an underlying pathophysiological disturbance. Treatment should be primarily directed at the underlying condition, not the acidosis. Thus, a key element of managing metabolic acidosis is determining the underlying cause. In most cases, metabolic acidosis is caused by increased plasma concentrations of pathologic anions and

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Summary. Drug causes of metabolic acidosis are numerous and their mechanisms are diverse. Broadly, they can cause metabolic acidosis with either a normal anion gap (e.g. drug-induced renal tubular acidosis) or an elevated anion gap (e.g. drug-induced lactic acidosis or pyroglutamic acidosis).

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For instance, the coexistence of vomiting-induced metabolic alkalosis may contribute to the rise in plasma pH in patients with metabolic acidosis. Common causes of metabolic acidosis include diabetic ketoacidosis (DKA), lactic acidosis, and hyperchloremic acidosis due to diarrhea or renal tubular acidosis.

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Metabolic disorders are disorders or defects of metabolism that cause Acidosis (1 drug); Adenosine Deaminase Deficiency (2 drugs); Alkalosis (1 drug)

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