Is etomidate safe to be used? We don't know – there is concern about the responses to intubation in high doses, but at the risk of hypotension. The
Background: Concerns over adrenal suppression caused by a single dose of etomidate for intubation led to limiting its use in trauma patients in 2024. Objective: The purpose of this study was to compare mortality, hypotension, and intensive care unit (ICU) and hospital length of stay (LOS) for trauma patients requiring intubation during periods of liberal vs. limited etomidate use.
Etomidate was given in 126 of 129 intubations. Ninety-five percent of patients (CI: 91–99) were given 20 mg of etomidate. Fifty-seven percent (
Compared with ketamine and etomidate, propofol was associated with better outcome in critically ill patients undergoing anesthesia for intubation. Even after adjusting for severity of illness prior to intubation, residual confounders cannot be excluded.
Neither etomidate or ketamine dose was significantly associated with post-intubation hypotension (primary outcome) or hypotension requiring fluids or
Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients. Cochrane Database
Independent variable studied: Etomidate and ketamine drug dose. Standard dosing is etomidate 0.3 mg/kg and ketamine 1.5 mg/kg. Design: Secondary analysis of data from a prospective registry. Exclusion: Intubation primarily performed with topical anesthesia, patients with missing data for the primary outcome, patient weight, etomidate/ketamine
Etomidate, with its stable cardiovascular profile, remains an induction agent of choice for emergency intubation, particularly in multitrauma
by MI El-Orbany 2024 Cited by 33intubation conditions achieved when small-dose succinylcholine is used to facilitate tracheal intubation. The doses of propofol, thiopental and etomidate
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