Probenecid: Acyclovir C max and AUC following a single dose of valacyclovir (1 gram) increased by 22% and 49%, respectively, after probenecid (1 gram). Thiazide Diuretics: The pharmacokinetics of acyclovir after a single dose of valacyclovir (1 gram) were unchanged by coadministration of multiple doses of thiazide diuretics.
Antacids: The pharmacokinetics of acyclovir after a single dose of valacyclovir (1 gram) were unchanged by coadministration of a single dose of antacids (Al3 or Mg ). Cimetidine: Acyclovir C max and AUC following a single dose of valacyclovir (1 gram) increased by 8% and 32%, respectively, after a single dose of cimetidine (800 mg).
20 mg/kg/dose (max 800 mg/dose) enterally four times daily. OR. Valacyclovir using dose below if patient is able to take pills. IV therapy for patients
infants 3-12 months of age. Consult ID and refer to neonatal guidelines for Acyclovir 20 mg/kg/dose (max 800 mg/dose) enterally tid. OR. Valacyclovir
The pharmacokinetics of acyclovir after a single dose of valacyclovir hydrochloride (1 gram) were unchanged by coadministration of a single dose of antacids (Al. 3 or Mg ). Cimetidine: Acyclovir C. max. and AUC following a single dose of valacyclovir hydrochloride (1 gram) increased by 8% and 32%, respectively, after a single dose of
Probenecid: Acyclovir C max and AUC following a single dose of valacyclovir (1 gram) increased by 22% and 49%, respectively, after probenecid (1 gram). Thiazide Diuretics: The pharmacokinetics of acyclovir after a single dose of valacyclovir (1 gram) were unchanged by coadministration of multiple doses of thiazide diuretics.
Acyclovir 10 mg/kg/dose IV q8h. Enteral therapy: Valacyclovir 20 mg/kg/dose (max 1000 mg/dose) enterally tid. (preferred if patient able to take pills). OR.
Acyclovir 20 mg/kg/dose (max 800 mg/dose) enterally four times daily. OR. Valacyclovir using dose below if patient is able to take pills. IV therapy for
Generally max dose of 12mg/kg. PD: Dose as CrCl 30 (IV q48h). DelafloxacinNF Valacyclovir. Adult. Herpes Simplex single-day treatment: 2 g PO q12h.
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