Fluoxetine cyp3a4 inhibitor

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Actual: Fluoxetine and paroxetine are potent CYP2D6 inhibitors, whereas fluoxetines main metabolite, norfluoxetine, has a moderate inhibitory effect on CYP3A4.
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have shown ketoconazole, a potent inhibitor of CYP3A4 activity, to be at least 100 times more potent than fluoxetine or norfluoxetine as an inhibitor of the

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If a strong CYP3A4 inhibitor and strong CYP2D6 inhibitor are coadministered or a known CYP2D6 poor metabolizer is receiving a concomitant strong CYP3A4 inhibitor, the ABILIFY dose should be reduced to one-quarter (25%) of the usual dose, . Strong CYP3A4 (eg, ketoconazole) or CYP2D6 (eg, fluoxetine) inhibitors will increase (2.6 7.1) (2.6 12.3)

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The selective serotonin reuptake inhibitors sertraline (weak CYP3A4 inducer) and fluoxetine (CYP2D6 inhibitor), and the anti-epileptic drug felbamate

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From in vitro data, fluoxetine is predicted to be a moderate inhibitor of CYP2D6, but a strong inhibitor of CYP2C19 and CYP3A4. However, in vivo fluoxetine

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The incidence of cannabis associated adverse effects may change following coadministration with fluoxetine. Fluoxetine is an inhibitor of CYP2C9 and CYP3A4, two

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CYP3A4 inhibitor, fluoxetine may increase levels of some statins, some BZDs, buspirone, and pimozide. As a. Page 26. CYP2D6 inhibitor, fluoxetine may increase

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The incidence of cannabis associated adverse effects may change following coadministration with fluoxetine. Fluoxetine is an inhibitor of CYP2C9 and CYP3A4

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The selective serotonin reuptake inhibitors sertraline (weak CYP3A4 inducer) and fluoxetine (CYP2D6 inhibitor), and the anti-epileptic drug felbamate

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such as fluvoxamine, fluoxetine, paroxetine, sertraline, and escitalopram?are weak inhibitors of CYP3A4.

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