HDL-raising drugs showed little or no effect. The thinking about raising HDL, might paradoxically increase the risk of heart disease.
Drugs which increase HDL as part of their lipid modifying Furthermore, currently available drugs do not robustly raise HDL. It
decrease LDL (bad) cholesterol and triglyceride levels. increase HDL (good) cholesterol levels. decrease the Total Cholesterol/HDL-Cholesterol Ratio (TC: HDL-C
by MS Kostapanos 2024 Cited by 342,4,9 Therefore, the examination of the effect of various hypolipidemic drugs on the HDL The dose-dependent increase in HDL-cholesterol levels, in our study
Diabetes Statins should not be discontinued if there is an increase in HDL-cholesterol (calculated as total cholesterol minus HDL-cholesterol), and
However, HDL cholesterol levels may be increased in some genetic disorders. If a high HDL level is found in a person who is not taking lipid-lowering drugs
However, low levels of HDL cholesterol have not been established as causative of this increase in risk. (See 'Low HDL cholesterol as an ASCVD risk factor' below and 'Effect of increasing HDL cholesterol on clinical outcome' below.) This topic will address clinical aspects of abnormal HDL (the particle) and HDL cholesterol.
by RS Rosenson Cited by 42As examples, simvastatin and rosuvastatin appear to raise HDL cholesterol more as the dose is increased, while the increase in HDL cholesterol
by A Pirillo 2024 Cited by 32Despite the established inverse correlation between HDL-C levels and cardiovascular risk, several clinical trials with HDL-C-increasing drugs (such as niacin
Isaac Asimov’s Three Laws of Robots does not apply here. Lots of possibilities.
Howard Campbell could be named after John W. Campbell who shaped sci-fi for the readers’ enjoyment.
Shame on HDL for not providing a sequel for his readers. Not nice to leave them hanging.
The story has a single focus. Expand the scope with subplots which become plots.
HDL, rewrite, edit and polish your story and sequel.
That’s how Sci-Fi Grandmasters are thusly honored by their works.
Best of luck in your endeavors.