MH crisis. Malignant hyperthermia (MH) is a rare, genetically Dantrolene dose response in malignant hyperthermia-susceptible (MHS)
by KPE Glahn 2024 Cited by 45Dosing schedule for dantrolene. We recommend an initial dose of 2–2.5 mg kg−1 of dantrolene in the treatment of an MH reaction. Our consensus
Instead, the authors proposed a cost-effective strategy stocking an initial dose of dantrolene on the unit with the plan to administer this initial dose while retrieving the MH cart from a central location in the event of an MH crisis. 7 The initial recommended dose of dantrolene is 2.5 mg/kg (total body weight). The Malignant Hyperthermia
Statement Median DI GRADE; 1. An early and appropriate dose of i.v. dantrolene is essential in the treatment of fulminant MH. 9: 0: 1a: 2. An initial dose of dantrolene 2 2.5 mg kg 1 should be used in the treatment of an MH reaction.
To treat an MH episode, an initial dose of dantrolene at 2.5 mg/kg is recommended, with a suggested upper limit of 10 mg/kg. If a patient of average weight (approximately 70 kg) were to require dantrolene at the upper dosing limit, then at least 700 mg of dantrolene would be needed.
Our study of 229 MH episodes with documented dantrolene doses found a wide range with an initial median dantrolene dose of 2.4 mg/kg and a total
by KPE Glahn 2024 Cited by 45Dosing schedule for dantrolene. We recommend an initial dose of 2–2.5 mg kg−1 of dantrolene in the treatment of an MH reaction. Our consensus
To treat an MH episode, an initial dose of dantrolene at 2.5 mg/kg is recommended, with a suggested upper limit of 10 mg/kg.
To treat an MH episode, an initial dose of dantrolene at 2.5 mg/kg is recommended, with a suggested upper limit of 10 mg/kg.
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