Naltrexone and gabapentin
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naltrexone plus active gabapentin (N=50), naltrexone plus placebo gabapentin (N=50), or placebo naltrexone and placebo gabapentin (N=50), using a double dummy placebo-controlled medication design. Naltrexone or its matching placebo was given as 25 mg for 2 days and then 50 mg/day for up to 16 weeks. Gabapentin (300-mg cap-
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Gabapentin also had preliminary efficacy as an add-on to naltrexone; in a trial of 150 alcohol-dependent subjects randomized to naltrexone (50 mg/day, n = 50) alone, naltrexone and gabapentin (up to 1,200 mg/day, n = 50) or double placebo (n = 50), the combined naltrexone/gabapentin group delayed the time to first HDD and decreased the number
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Combining gabapentin and naltrexone may also help counteract some naltrexone side effects, such as insomnia and mood problems. 7 Finally, gabapentin can ease initial alcohol withdrawal symptoms and make it easier for people to transition to daily naltrexone or the Sinclair Method.
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JThe addition of gabapentin to naltrexone improved drinking outcomes compared with naltrexone alone in heavy drinkers during
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6 weeks of naltrexone (50 mg/day) plus gabapentin (up to 1,200 mg/day), followed by 10 weeks of naltrexone alone. Placebo. All participants received medical management. Over the first 6 weeks, those receiving naltrexone plus gabapentin had a longer interval to heavy drinking than those taking only naltrexone.
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Poor sleep was associated with more drinking in the naltrexone-alone group but not in the naltrexone-gabapentin group, while a history of alcohol withdrawal was
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Can Gabapentin Be Taken with Naltrexone? Gabapentin can be taken with naltrexone to help treat alcohol dependence. In fact, studies showed that when gabapentin is taken with naltrexone, people abstained from alcohol longer and felt more control over drinking urges than if they took naltrexone alone or a placebo.
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taking naltrexone plus gabapentin Participants in the naltrexone-alone group were more likely to drink heavily during periods in which they
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Combining gabapentin and naltrexone may also help counteract some naltrexone side effects, such as insomnia and mood problems. Finally, gabapentin can ease
Comments
This story is great fun; it's sexy too. I especially enjoyed the heroine/narrator's personality, including her fairly strong—but decidedly quirky—ethical principles. I do feel sorry for her uncle, though. He got left out of the action entirely. Perhaps there will be a Part 3? Fine with me, if so.
Not much good news. Went to my neuropathist on Wednesday for a series of tests. 'Yes', I have nerve damage and 'no', the doctor looking at the results couldn't understand why. Essentially, they ran an escalating electric current from various spots on my lower leg and foot to toes to see how I responded. I highly recommend this as a means of torture.
On the downside, I am becoming resistant to my pain medication, so life sucks coming and going. My psychiatrist upped my Gabapentin from 300 Mg to 400 Mg [3x a day] and it isn't helping. Woot? I'd kill for a decent night's sleep.
Thank you for asking. I really wish I had better news.
James aka FinalStand
On the beneficial side, I know where I want to take Chapter 5 in this tale. I have much of it mapped out in my mind.
They travel to the mainland in pursuit of the Atlanteans ... which completes the 13th Circle of the Black Witches Coven (whoops!) ~ giving the descendants of the other 7 the power they have been long denied. There is still the government task force on the serial killings to deal with plus the on-going conflict with the White Coven. The main mystery remains ~ what was an Atlantean doing breeding with an Abenaki and teaching at least one half-breed offspring magic over 400 years ago ... and why would a normally amoral Altantean 'noble' be interested in said half-breed today?
God - sometimes I really wish I had a clone ... or two.
James aka FinalStand