Drugs that increase hdl

While higher HDL levels are correlated with lower risk of cardiovascular diseases, no medication used to increase HDL has been proven to improve health. [2] [32] As of 2024, numerous lifestyle changes and drugs to increase HDL levels were under study. [2]

by A Pirillo 2024 Cited by 32The treatment with pitavastatin not only increased HDL-C levels, but also increased the phospholipid content of HDL, increased the HDL efflux capacity and their

There are several basic mechanisms by which a drug can raise HDL cholesterol: an increase in the uptake of cholesterol from tissues by HDLs; an increase in the transfer of cholesterol from other lipoproteins to HDLs; a reduction of the rate of transfer of cholesteryl esters from HDLs to the liver; and a reduction of cholesteryl ester transfer

00 Increasing HDL 0:22 What is HDL? 1:42 Benefits of HDL 1:55 How to increase No medication has been found to increase HDL and improve health.

However, low levels of HDL cholesterol have not been established as causative of this increase in risk. (See 'Low HDL cholesterol as an ASCVD risk factor' below and 'Effect of increasing HDL cholesterol on clinical outcome' below.) This topic will address clinical aspects of abnormal HDL (the particle) and HDL cholesterol.

Drugs which increase HDL as part of their lipid modifying Furthermore, currently available drugs do not robustly raise HDL. It

Fibrates, e.g, carboxylic acid derivatives 1–3 (Scheme 1), are a class of drugs that increase HDL cholesterol (HDL-C) via activation of PPARα, as indicated by

Niacin has been promoted for decades as a high-density lipoprotein (HDL)-raising drug. increasing HDL-P. Niacin is an LDL-lowering drug, specifically

However, HDL cholesterol levels may be increased in some genetic disorders. If a high HDL level is found in a person who is not taking lipid-lowering drugs