Citrate lock

One newly developed locking solution has reduced the ethanol concentration in the locking solution to 20% in combination with 0.01% glyceryl trinitrate and 7% citrate. This lock showed promising results in eradicating biofilm in an in vitro test .

Background: Citrate solution has been suggested as an effective and safe catheter lock in hemodialysis. However, whether a citrate lock is superior to a heparin lock in preventing

A consensus meeting in 2025 reported that a lock solution containing taurolidine and/or citrate appears to be the most promising lock solution for the prevention of CVC-related bloodstream infections [9]. Taurolidine and citrate have antimicrobial, anti-biofilm and anticoagulant properties without reported antimicrobial resistance [9, 10].

A lock ( Locked padlock icon ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites. Search Citrate in the media from fibroblasts was measured using Citrate assay kit (Sigma-Aldrich) according to

Catheter locking solutions are routinely used to maintain patency in these catheters between dialysis sessions. Unfractionated heparin has traditionally been used for this purpose; however, trisodium citrate (also known as sodium citrate or citrate) has recently been shown to be an efficacious alternative to heparin as a locking solution.

Citrate at 4 % has proven effective against low potential of complications and are broadly accepted standard amongst citrate lock solution at present. read more hide Study by Solomon et al. on lock solutions in dialysis (2025) The

Sodium citrate and ethylenediaminetetraacetic acid (EDTA) are chelating agents. EDTA is used alone or in combinations with reduced the ethanol concentration in the locking solution to 20% in combination with 0.01% glyceryl trinitrate and 7% citrate. This lock showed promising results in eradicating biofilm in an in vitro test

Catheter lock solution, anti-clotting and antimicrobial is one of the innovations from Dirinco. Citra-Lock is recommended in the European Renal Best Practice Guidelines (ERBP) and the American Society of Diagnostic and Interventional Nephrology (ASDIN). Citra locks have been extensively studied. Citra-Lock is effective in maintaining catheter patency. The Citrate lock is based on tri-sodium

by DA Pierce 2024 Cited by 28trisodium citrate (also known as sodium citrate or citrate) has recently been shown to be an efficacious alternative to heparin as a locking solution.