Warfarin: Clinical Impact: Increased INR and prothrombin time in patients receiving PPIs, including omeprazole, and warfarin concomitantly. Increases in INR and prothrombin time may lead to abnormal bleeding and even death. Intervention: Monitor INR and prothrombin time and adjust the dose of warfarin, if needed, to maintain target INR range
Bactrim is known to increase warfarin sensitivity and push the INR higher. Reducing the warfarin dose in conjunction with a short interval until repeat INR
Selected warfarin drug-drug interactions. Warfarin related Links. Decreased warfarin effect (Lower INR). Increased warfarin effect (POTENTIATION).
INR measures the time it takes your blood to clot. This is increased by taking warfarin, which, in turn, increases the INR. The higher the INR, the longer it
Medications that interact with warfarin by increasing the INR and chances of a catastrophic bleed, or by decreasing the INR and exposing patients to the risk
Warfarin. Clinical Impact: Increased INR and prothrombin time in patients receiving PPIs, including omeprazole, and warfarin concomitantly. Increases in INR
INR) of warfarin by increasing the exposure of warfarin. levothyroxine liothyronine lovastatin medroxyprogeste rone mefenamic.
This is a partial list of medications that may increase or decrease warfarin effect on the INR. Interaction of warfarin with drugs, natural substances, and
Selected warfarin drug-drug interactions. Warfarin related Links. Decreased warfarin effect (Lower INR). Increased warfarin effect (POTENTIATION).
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